Between Molecules and Challenges

The Path of Medical Biology in Cuba

Introduction: An Educational Revolution in Medical Sciences

Cuban medical education has undergone profound transformations since 1959, when health was declared a universal and free right. This commitment required an educational model capable of training doctors with preventive-promotional thinking, integrating teaching, research and clinical practice. In 2013, the Study Plan "D" was born, an innovative curricular design that reorganizes the Biological Bases of Medicine (BBM) as a fundamental axis for medical training. At the Puerto Padre Branch, the implementation of this plan revealed unexpected challenges, especially in Molecular Biology, where academic performance became a thermometer of educational effectiveness 1 .

Plan "D": Scientific Integration as the Backbone

Fundamentals and Structure

Plan "D" emerged to respond to international standards of medical education (such as those of the World Federation for Medical Education, WFME). Its innovation lies in:

Basic-clinical integration

Links basic disciplines like Molecular Biology with clinical applications from the first year.

Longitudinal curricular strategies

The BBM discipline spans three semesters, structured into seven subjects based on levels of biological organization.

Socio-medical approach

Combines scientific training with primary care and community health 1 .

Molecular Biology: The Achilles Heel

In the first semester, students face three key subjects:

  1. Molecular Biology (human molecules and their functions).
  2. Cell, Basic Tissues and Integumentary System.
  3. Human Ontogeny and Osteomyoarticular System (SOMA).

Performance data from the University of Medical Sciences of Guantánamo (2016-2017) revealed an alarming gap:

Subject Promotion Rate (%)
Molecular Biology 73.6
Cell, Basic Tissues and Integumentary System 82.4
Human Ontogeny and SOMA 80.2

Source: 1

This disparity revealed structural problems in teaching abstract concepts such as DNA replication, gene expression and cell signaling.

Diagnosis of a Problem: Why Does Molecular Biology Fail?

Pedagogical and Logistical Gaps

A study in Guantánamo identified critical weaknesses:

Shortage of specialized teachers

In Basic Biomedical Sciences (CBB).

Traditional teaching methods

Master classes with little clinical linkage.

Lack of resources

Laboratories without equipment for genetic experiments or PCR 1 .

The Cognitive Challenge

"Students must visualize invisible processes (e.g., RNA translation) and relate them to complex diseases like cancer. Without clinical analogies, this is reduced to memorizing incomprehensible routes" 1 .

Innovative Solutions: Project-Based Learning

Transformative Methodology

In Holguín, an alternative was proposed: Project-Based Learning (PBL). This model:

Integrates academia, research and practice

Example: Genetic sequencing projects linked to real patient cases.

Promotes multidisciplinary work

Biologists, doctors and students collaborate in molecular diagnostics.

Uses accessible technology

Digital PCR or CRISPR simulators when reagents are lacking 2 .

Didactic Tools Kit

Resource Educational Function
PCR Simulators Teaches DNA amplification without expensive reagents.
Virtual clinical cases Links genetic mutations with real symptoms.
Community projects Example: Analysis of hereditary predisposition to diabetes in local families.

Source: 2

Results: From Theory to Effective Practice

Experience in Holguín

A project in Molecular Biology achieved:

Increased knowledge retention

From 68% to 89% in practical evaluations.

Improved clinical skills

Students interpreted genetic tests for early diagnoses.

Student scientific publication

Two teams published results in local journals 2 .

Comparative Table: Traditional Method vs. PBL

Indicator Traditional Method Project-Based Learning
Approval rate 73.6% 89.2%
Participation in research 12% 68%
Student satisfaction 45% 92%

Source: 2

Conclusion: Towards Genomic Medical Education

The crisis in Molecular Biology under Plan "D" is not a failure, but an opportunity to innovate. Cuba is moving towards a model where:

  • Genomics becomes part of primary care: Doctors capable of using molecular data in communities.
  • Universities train "physician-scientists": Professionals who research while they heal.

As the Genomic Medicine program at the University of Guadalajara points out, this requires doctorates that merge molecular biology with clinical management .

Did you know?

Plan "D" includes 10 stays of Comprehensive General Medicine, linking each molecular advance with community health from the first year 1 .

References