Research Articles
Bayesian Lasso for Genomic Prediction: A Complete Guide for Precision Medicine Research
This comprehensive guide explores the implementation of Bayesian Lasso (LASSO) for genomic prediction in biomedical research and drug development.
BayesDπ vs. BayesCπ for QTL Mapping: Which Model Wins When QTL Numbers Are Unknown?
Accurate genetic mapping of quantitative trait loci (QTL) is critical for complex disease research and precision medicine, but the unknown number of causal variants poses a significant challenge.
BayesA vs GBLUP: Choosing the Best Genomic Prediction Model for Plant Disease Resistance
This article provides a comprehensive comparison of the BayesA and GBLUP (Genomic Best Linear Unbiased Prediction) models for genomic selection of disease resistance traits in plants.
Bayesian vs. GBLUP Genomic Selection: A Comparative Analysis for Porcine Carcass Trait Improvement
This article provides a comprehensive analysis of BayesA and GBLUP methodologies for genomic selection in pig breeding, focusing on carcass traits like backfat thickness, loin muscle area, and lean meat...
Bayesian Alphabet in Genetics: Demystifying BayesA, BayesB, and BayesC for Major and Minor QTL Mapping
This article provides a comprehensive guide for researchers, scientists, and drug development professionals on applying Bayesian alphabet methods—specifically BayesA, BayesB, and BayesC—for mapping both major and minor quantitative trait loci...
BayesA Prior Specification and Parameter Tuning: A Practical Guide for Genomic Prediction and Biomarker Discovery
This article provides a comprehensive guide to BayesA prior specification and hyperparameter tuning, tailored for researchers, scientists, and drug development professionals working with genomic prediction, biomarker identification, and complex trait...
BayesA Genomic Prediction: A Beginner's Guide for Biomedical Researchers
This article provides a comprehensive, step-by-step guide to implementing the BayesA methodology for genomic prediction, tailored for researchers and drug development professionals.
BayesA vs BayesB vs BayesC: A Comprehensive Guide to Genomic Selection Priors for Biomedical Research
This article provides a comprehensive, practical guide to BayesA, BayesB, and BayesC prior distributions for researchers and drug development professionals in the biomedical field.
False Discovery Rates in Differential Expression Analysis: A Practical Guide for Biomarker and Drug Target Validation
This article provides a comprehensive guide to understanding, controlling, and validating False Discovery Rates (FDR) in differential expression analysis for genomics and transcriptomics studies.
VUS Discordance in Genomic Medicine: A Critical Analysis of Inter-Laboratory Classification Concordance and Its Impact on Clinical Decision-Making
This article provides a comprehensive analysis of Variants of Uncertain Significance (VUS) classification concordance across clinical laboratories, a critical challenge in precision medicine.